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What is the correct way to inoculate the hepatitis B vaccine?

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Most HBV carriers in China come from neonatal and childhood infections. This shows that neonatal prevention is particularly important, all neonates should be inoculated with hepatitis B vaccine. This is because the newborn is the most immune to hepatitis B virus, and the immune function is not sound, once dyed, it is difficult to clear the virus and become a hepatitis B virus carrier. Secondly, preschool children should also be inoculated. Third is the spouses of HBsAg positive people and other people engaged in the dangerous occupation of HBV infection, such as people with close contact with blood, medical staff, hemodialysis patients, and so on. Fourth people who were accidentally exposed to hepatitis B virus, if they were injured by needle of HBsAg positive blood, or were splashed in the conjunctiva or oral mucosa by HBsAg positive blood, input HBsAg positive blood and so on, all should be vaccinated against hepatitis B vaccine.

The whole course of hepatitis B vaccination was 3 needles. According to the 0, 1, 6 month procedure, that is, after inoculation of first vaccinations, second and 3 vaccinations were injected at intervals of 1 and 6 months. The earlier the inoculation of hepatitis B vaccine is, the better the vaccination is required within 24 h after birth. The inoculation site of the newborn is the lateral muscles of the thigh, and the children and adults are injected into the middle muscles of the upper arm deltoid. The protective rate of hepatitis B vaccine blocking mother to child transmission was 87.8%.

(1) if the parents of the newborns have no hepatitis B, the newborns should be given 1 branches of the gene engineering hepatitis B vaccine as soon as possible (24 hours). The newborn is the lateral lateral muscle of the anterior thigh for 1 months, 1 more, and 6 months later, 1, and 3, the scheme is called 0, 1, 6; children If the three system examination of hepatitis B is negative and the aminotransferase is normal, the hepatitis B vaccine can be vaccinated according to the 0, 1 and 6 scheme (the general dose of adult doubles). The immunization success rate is more than 90%. The sign of immunization success is that the hepatitis B surface antibody turns positive. The protection time is generally at least 12 years. The inoculant can check the hepatitis B three system regularly. As long as the surface antibody still exists, the immune ability is still proved.

(2) for the mother of the mother for the simple surface antigen positive newborn, the single use of hepatitis B vaccine can achieve more satisfactory results, the use of hepatitis B vaccine is still 0, 1, 6, it is reported that the first needle can hit 2 (10 microgram /l milliliter) effect is better.

(3) for newborns with double positive hepatitis B virus surface antigen and e antigen, the best combination of HBV and HBV immunoglobulin and hepatitis B vaccine is the best combination. The specific method is that the newborns are injected with 2 high effective hepatitis B immunoglobulin (1, 200 international units, 200 international units) and 3 hepatitis B vaccines (10 micrograms each, 2, 3, and 1 in May), and 1 high effective hepatitis B immunoglobulin, and 3. The hepatitis B vaccine (15 micrograms per time, 1 times after birth and 1 times in January and June), the success rate of 2 protection schemes was over 90%.

(4) for persons exposed to hepatitis B virus (HBV), after accidental exposure to the blood and body fluids of HBV infected persons, the following methods can be treated according to the following methods: HBsAg, anti -HBs, ALT and so on should be detected immediately in A. serological examination and rechecked in 3 and 6 months. B. active and passive immunization, such as those vaccinated with hepatitis B vaccine and known to be resistant to -HBs or more than 10 mIU/ml, can be treated without special treatment. If not inoculated with hepatitis B vaccine, or inoculated with hepatitis B vaccine, it is resistant to -HBs.

The vaccination of hepatitis B vaccine should be carried out in accordance with specific conditions and compliance with medical advice. After vaccination, the general reaction is mild, and few people may appear low fever, red swelling and pain in the inoculation area, and usually disappear within 1~2 days. The safety of the use of hepatitis B vaccine has a reliable guarantee. From the immune effect, a large number of studies have shown that the positive rate of antibody in the recipient is above 90%, and the protection rate is more than 80% for three years after vaccination. Moreover, the vaccine HbsAg content is sufficient and stable as long as the vaccine combination method is suitable, and the effect of vaccine immunization blocking mother to child transmission is also ten points.


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